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    Anal fissures are caused by trauma to the anus and anal canal. The cause of the trauma usually is a bowel movement, and many people can remember the exact bowel movement during which their pain began. The fissure may be caused by a hard stool or repeated episodes of diarrhea. Occasionally, the insertion of a rectal thermometer, enema tip, endoscope, or ultrasound probe for examining the prostate gland can result in sufficient trauma to produce a fissure. During childbirth, trauma to the perineum the skin between the posterior vagina and the anus may cause a tear that extends into the anoderm.
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    Is topical nifedipine effective for chronic anal fissures?

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    Anal Fissure - Symptoms, Causes and Treatment

    AIM: To investigate the efficacy of topical application of 0. The patients were encouraged to follow a high-fiber diet and assessed at 2, 4 and 8 wk post-treatment. The healing of fissure and any side effects were recorded. The patients were subsequently followed up in the outpatient clinic for one year and contacted by phone every three months thereafter, while they were encouraged to come back if symptoms recurred. Of the remaining four unhealed patients
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    Topical Nifedipine Plus Lidocaine Gel Effective for Anal Fissures

    Clinical Question: Is a topical gel containing nifedipine and lidocaine effective in the treatment of chronic anal fissures? Synopsis: Treatment of chronic anal fissures includes stool softeners, topical anesthetics, and nitroglycerin ointment. Many patients are unable to tolerate the adverse affects e. This study involved consecutive patients with chronic anal fissures. Inclusion criteria were defined by clinical examination and a history of anal pain on defecation for at least two months despite treatment with stool softeners and topical anesthetic agents.
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